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Iuliana Ionita-Laza

biography

My research interests lie at the interface between statistics and genomics. I am particularly interested in the development of statistical and machine learning methods for the analysis of high-dimensional genetic and functional genomic data. I am also involved in using such methods to understand the genetic basis of complex diseases and traits, including autism spectrum disorders, schizophrenia, and Alzheimer's disease.

subjects

Chronic Disease Genetics Global Health

education

PhD, 2006, Courant Institute of Mathematical Sciences, NYU

The editorial staff

Associate Editor, Biometrics Associate Editor, Life Sciences Statistics

Honors & awards

Janet-Fabri-Preis, Courant Institute of Mathematical Sciences, 2007 Dean's Dissertation Fellowship, New York University, 2005-2006

areas of expertise

Bioinformatics, data science, predictive modeling / machine learning, genetics, mental health

Select publications

I Ionita-Laza, NM Laird On the Optimal Design of Studies to Detect Genetic Variants Statistical Applications in Genetics and Molecular Biology 2010 I Ionita-Laza, J. Buxbaum, N. Laird and C. Lange A new test strategy to identify rare variants at risk or protective effect on the disease PloS Genetics 2011 Iuliana Ionita-Laza, Christoph Lange, Nan Laird About a method for counting the number of invisible variants in the human genome Proc Natl Acad Sci 106 5008-5013 2009 David Fardo, Iuliana Ionita-Laza, Christoph Lange On quality control measures in genome-wide association studies: A test to assess the genotyping quality of individual subjects in family-based association studies and an application to the HapMap data Plos Genetics 2009 Lars Bertram, Christoph Lange et al., Iuliana Ionita-Laza, et al. R Tanzi genome-wide association analysis reveals putative susceptibility to Alzheimer's disease in addition to APOE American Journal of Human Genetics 83 623-632 2008 Jinbo Fan *, Iuliana Ionita-Laza *, et al., Nan Laird, Jordan Smoller Linkage Disequilibrium Mapping of das Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus Neuropsychiatric Genetics 2009 Iuliana Ionita-Laza, Nan Laird, Benjamin Raby, Scott Weiss, Christoph Lange On the frequency of copy number variants Bioinformatics 24 2350-2355 2008 Iuliana Ionita-Laza, Angela Rogers, Christoph Lange, Benjamin Raby, Charles Lee Genetic Association Analysis of Copy Number Variation in the Pathogenesis of Human Disease Genomics 93 22.-26. 2009 Iuliana Ionita-Laza, George Perry, Benjamin Raby, Barbara Klanderman, Charles Lee, Nan Laird, Scott Weiss, Christoph Lange On the analysis of copy number variations in genome-wide association studies: A translation of the family-based association test Genetic Epidemiology 32 273-284 2008 Iulian a Ionita- Laza, Matthew McQueen, Nan Laird, Christoph Lange Genomewide Weighted Hypothesis Testing in Family-Based Association Studies, with an application for a 100K scan American Journal of Human Genetics 81 607-614 2007 Iuliana Ionita, Raul-Sam Daruwala, Bud Mishra mapping of tumor suppressor genes using multipoint statistics from copy number variation data American Journal of Human Genetics 79 13-22 2006 Iuliana Ionita, Shaw-Hwa Lo Multilocus linkage analysis of affected sibling pairs Human inheritance 60 227-240 2005

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