My research interests lie at the interface between statistics and genomics. I am particularly interested in the development of statistical and machine learning methods for the analysis of high-dimensional genetic and functional genomic data. I am also involved in using such methods to understand the genetic basis of complex diseases and traits, including autism spectrum disorders, schizophrenia, and Alzheimer's disease.
The editorial staff
Honors & awards
areas of expertiseBioinformatics, data science, predictive modeling / machine learning, genetics, mental health
I Ionita-Laza, NM Laird On the Optimal Design of Studies to Detect Genetic Variants Statistical Applications in Genetics and Molecular Biology 2010 I Ionita-Laza, J. Buxbaum, N. Laird and C. Lange A new test strategy to identify rare variants at risk or protective effect on the disease PloS Genetics 2011 Iuliana Ionita-Laza, Christoph Lange, Nan Laird About a method for counting the number of invisible variants in the human genome Proc Natl Acad Sci 106 5008-5013 2009 David Fardo, Iuliana Ionita-Laza, Christoph Lange On quality control measures in genome-wide association studies: A test to assess the genotyping quality of individual subjects in family-based association studies and an application to the HapMap data Plos Genetics 2009 Lars Bertram, Christoph Lange et al., Iuliana Ionita-Laza, et al. R Tanzi genome-wide association analysis reveals putative susceptibility to Alzheimer's disease in addition to APOE American Journal of Human Genetics 83 623-632 2008 Jinbo Fan *, Iuliana Ionita-Laza *, et al., Nan Laird, Jordan Smoller Linkage Disequilibrium Mapping of das Chromosome 6q21-22.31 Bipolar I Disorder Susceptibility Locus Neuropsychiatric Genetics 2009 Iuliana Ionita-Laza, Nan Laird, Benjamin Raby, Scott Weiss, Christoph Lange On the frequency of copy number variants Bioinformatics 24 2350-2355 2008 Iuliana Ionita-Laza, Angela Rogers, Christoph Lange, Benjamin Raby, Charles Lee Genetic Association Analysis of Copy Number Variation in the Pathogenesis of Human Disease Genomics 93 22.-26. 2009 Iuliana Ionita-Laza, George Perry, Benjamin Raby, Barbara Klanderman, Charles Lee, Nan Laird, Scott Weiss, Christoph Lange On the analysis of copy number variations in genome-wide association studies: A translation of the family-based association test Genetic Epidemiology 32 273-284 2008 Iulian a Ionita- Laza, Matthew McQueen, Nan Laird, Christoph Lange Genomewide Weighted Hypothesis Testing in Family-Based Association Studies, with an application for a 100K scan American Journal of Human Genetics 81 607-614 2007 Iuliana Ionita, Raul-Sam Daruwala, Bud Mishra mapping of tumor suppressor genes using multipoint statistics from copy number variation data American Journal of Human Genetics 79 13-22 2006 Iuliana Ionita, Shaw-Hwa Lo Multilocus linkage analysis of affected sibling pairs Human inheritance 60 227-240 2005Back to top