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W. Ian Lipkin

biography

W. Ian Lipkin, MD, is internationally recognized as the authority on the use of molecular methods to detect pathogens. Dr. Lipkin has over 30 years of diagnostic, microbial detection and outbreak response experience, has mentored and trained more than 30 students and postdocs, and leads a team of over 65 researchers, postdocs, and research and support staff in New York City and another 150 worldwide. In the 1980s, Dr. Lipkin AIDS-associated immunologic abnormalities and inflammatory neuropathy, which he showed can be treated with plasmapheresis, and showed that exposure to viral infections in early life affects neurotransmitter function. He was the first to use purely molecular methods to identify an infectious agent, developed the MassTag PCR and GreeneChip technology, and pioneered the use of high-throughput sequencing in pathogen discovery. He and his team linked the West Nile virus as the cause of the encephalitis epidemic in New York in 1999 and discovered or characterized more than 500 infectious agents, including Borna virus, West Nile virus and LuJo Virus and human rhinovirus C from WHO and the People's Republic of China during the 2003 SARS outbreak and is currently advising the Kingdom of Saudi Arabia on addressing the MERS challenge. He also directs large programs focused on autism and chronic fatigue syndrome, which postulate that gene-environment interactions such as infection and poisoning cause disease. Dr. Lipkin has been featured by the New York Times, Los Angeles Times, Discover Magazine, Nature Medicine, History Channel, National Geographic, CNN, Fox, National Public Radio, Wired, and the Huffington Post. He was senior scientific advisor for the Soderbergh film Contagion and is working on a new series for AMC.

subjects

Chronic Illness Infectious Disease

education

Others, 1984, residency in neurology Others, 1981, residency in internal medicine, 1978, Rush University BA, 1974, Sarah Lawrence College Lawrence

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Postman Affiliations

Director, Center for Infection and Immunity

The editorial staff

mBio Offene Biology

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Columbia Affiliations

Senator, Member of the University Senate, Member of the Education Committee of the Senate, Member of the Committee for Honors and Prizes, Advisory group of the dean

Academic appointments

John Snow Professor, Epidemiology, Professor of Neurology and Pathology, and Cell Biology Scientific Director, Joint Research Laboratory for Pathogen Discovery Daldorf Affiliated Research Physician, Wadsworth Center

Other affiliations

Fellow, American Academy of Microbiology Fellow, American Association for the Advancement of Science (AAAS) Mitglied, Association of American Physicians Fellow, Infectious Disease Society of America Fellow, American Academy of Neurology

Honors & awards

Silverstein Lecturer, Northwestern University (2017) Medel Medal, Villanova University (2014) Drexel Prize in Translational Medicine (2013) Senior Scholor in Global Infectious Diseases, Ellison Medical Foundation (2002) Pew Scholar, Biomedical Sciences (1991)

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areas of expertise

Autism, neurodevelopmental disorders, emerging infections, epidemics, infectious diseases, pathogen discovery

Choose Urban Health Activities

Rodent Pathogen Monitoring in NYC : Principal researcher on a project to determine the microflora of rats and mice near densely populated and high-traffic areas in New York City.

Choose Global Activities

Gene-Environment Interactions in an Autism Birth Cohort , Norway: Dr. Lipkin is the lead investigator of an anticipated birth cohort of 100,000 women, their children and partners focused on determining the epidemiology, natural disease course and pathogenesis of autism spectrum disorders. Training and treating SARS outbreaks , China (People's Republic): At the height of the SARS outbreak in 2003, Dr. At the invitation of the WHO, the Chinese Minister of Science and Technology and the Vice President of the Chinese Academy of Science, Lipkin carries 10,000 test kits by hand to Beijing and trained clinical microbiologists in their correct use. Evaluation of the MERS outbreak , Saudi Arabia: Dr. Lipkin was the first outside researcher invited by the Ministry of Health in Saudi Arabia to help identify reservoirs and vectors for the transmission of the MERS coronavirus.

Select publications

Briese T, Kapoor A, Mischra N, Jain K, Kumar A, Jabado OJ, Lipkin WI (2015) Virom-Capture-Sequencing (VirCapSeq) enables sensitive virus diagnosis and comprehensive virus analysis. mBio. September 22; 6 (5): e01491-15. Alagaili AN, Briese T, Mishra N, Kapoor V, Sameroff SC, de Wit E, Munster VJ, Hensley LE, Zalmout IS, Kapoor A, Epstein JH, Karesh WB, Daszak P, Mohammed OB, Lipkin WI (2014) Middle East Respiratory syndrome coronavirus infection in dromedaries in Saudi Arabia. mBio, 5 (2): e00884-14. Lipkin WI (2013) The Changing Face of Pathogen Monitoring and Detection. Nature Rev Microbiol, 11: 133. Anthony SJ, Epstein JH, Murray KA, Navarrete-Macias I, Zambrana-Torrelio CM, Solovyov A, Ojeda-Flores R, Arrigo NC, Islam A, Khan SA, Hosseini P, Bogich TL, Olival KJ, Sanchez-Leon MD, Karesh WB, Goldstein T, Luby SP, Morse SS, Mazet JAK, Daszak P, Lipkin WI (2013) A strategy for estimating unknown viral diversity in mammals. mBio, 4: 5 e00598-13 Alter HJ, Mikovits JA, Switzer WM, Ruscetti FW, Lo SC, Klimas N, Komaroff AL, Montoya JG, Bateman L, Levine S, Peterson D, Levin B, Hanson MR, Genevai A, Bhat M, Zheng H, Wang R, Li B, Hung GC, Lee LL, Sameroff S, Heneine W, Coffin J, Hornig M, Lipkin WI (2012) A multicenter blinded analysis shows no association between chronic fatigue syndrome / myalgic encephalomyelitis and either with the xenotropic murine leukemia virus-related virus or the polytropic murine leukemia virus. mBio, 3: e00266-12. Palacios G, Druce J, Du L, Tran T, Birch C, Briese T, Conlan S, Quan PL, Hui J, Marshall J, Simons JF, Egholm M, Paddock CD, Shieh WJ, Goldsmith CS, Zaki SR, Catton M , Lipkin WI (2008) A new arenavirus in a cluster of deadly transplant-associated diseases. The New England Journal of Medicine. March 6; 358 (10): 991-8. Cox-Foster DL, Conlan S, Holmes EC, Palacios G, Evans JD, Moran NA, Quan PL, Briese T, Hornig M, Geiser DM, Martinson V, vanEngelsdorp D, Kalkstein AL, Drysdale A, Hui J, Zhai J, Cui L, Hutchison SK, Simons JF, Egholm M, Pettis JS, Lipkin WI (2007) A metagenomic study of microbes in the honeybee colony collapse disorder. Science. Oct 12; 318 (5848): 283-7. Briese T, Jia X-J, Huang C, Grady LJ, Lipkin WI (1999) Identification of a Kunjin / West Nile-like flavivirus in the brains of New York encephalitis patients. Lancet, 354: 1261. Lipkin WI, Travis GH, Carbone KM, Wilson MC (1990) Isolation and characterization of cDNA clones of the causative agent of Borna disease. Proc Natl Acad Sci USA, 87: 4184. Lipkin WI, Parry G, Kiprov D, Abrams D (1985) Inflammatory neuropathy in homosexual men with lymphadenopathy. Neurology, 35: 1479.

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